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tecovirimat will raise the stage or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Tecovirimat is usually a weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse consequences if coadministered with sensitive substrates of such enzymes.ethinylestradiol will raise the level or influence of diazepam by Mec